Caverject 20 Micrograms Powder For Solution For Injection

Extreme caution is required in patients with caverject heart disease, uncontrolled hypertension, cerebral ischaemia, and in subjects cavefject monoamine oxidase inhibitors. Caverject view the caevrject to a medicine you must sign up and log in. Penile fibrosis, including angulation, cavernosal fibrosis, fibrotic nodules and Peyronie's disease may occur following the intracavernosal administration of alprostadil. Caverject Impulse Indication: If still unsuccessful, intracavernous injection of alpha-adrenergic medication is recommended. Name of the medicinal product 2. Caverject Caverject. The risk of benzyl caverejct toxicity depends on the quantity administered and the hepatic capacity to detoxify the chemical. The lowest effective dose should be used. The maximum dose of phenylephrine caevrject be 1 mg, or adrenaline micrograms 5 ml of the solution. The risk of benzyl alcohol toxicity depends on the quantity administered and the hepatic capacity to detoxify the chemical. Penile fibrosis, including angulation, cavernosal fibrosis, fibrotic nodules and Peyronie's disease may occur following the intracavernosal administration of alprostadil, caverject. Scrotal or testicular disorders- This can involve pain, redness or swelling. The dose of Caverject should be individualised for each patient by careful titration under supervision by a physician. As an aid to aetiologic diagnosis. Pharmaceutical form 4. A half inch, 27 to 30 gauge needle is generally recommended. Drugs used caverjsct erectile dysfunction ATC code: Regular follow-up of patients, with careful examination of the penis, is strongly caverject to detect signs of penile fibrosis or Peyronie's caverject. Should an ensuing erection persist for more than one hour detumescent therapy please refer to Section 4. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Caveruect Scheme at www. Name of the medicinal product 2. As with all superfine needles, the possibility of needle breakage exists. Underlying treatable medical causes of erectile dysfunction should be diagnosed and treated prior to initiation of therapy with alprostadil. Single pack containing a 5 ml clear, colourless, glass vial of Caverject 20 micrograms powder with a bromobutyl rubber stopper and an aluminium overseal cacerject polypropylene flip-off cap Packs also each contain a syringe of solvent, a sterile 22G and caverject 30G needle plus a preinjection swab.

The entire caverject can be injected or for better flexibility of dosing, quarterly increments can be injected. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at www. Single pack containing a 5 ml clear, colourless, glass vial of Caverject 20 micrograms powder with a bromobutyl rubber stopper and an aluminium overseal with polypropylene flip-off cap Packs also each contain a syringe of solvent, a sterile 22G and a 30G needle plus a preinjection swab. Pharmacia AB Caverject Impulse Indication: This information is intended for use by health professionals. Anal Bleeding - caverject - Dr Joe: Enter medicine name caverject company Start typing to retrieve search suggestions. What to pack for hospital. Patients should be instructed to report to a physician any erection lasting for a prolonged time period, such as 4 hours or longer. Fit the 22 gauge needle to the syringe. Alprostadil should not be used in men for whom sexual activity is inadvisable or contraindicated. Caverject Impulse contains the active component alprostadil which is used in the treatment of male erectile dysfunction. Qualitative and quantitative composition 3. Blood pressure and pulse should be continuously monitored during the procedure. Jump over to the doctors caverject platform. The adverse drug reactions are listed in order of decreasing medical seriousness within each frequency category and caverject organ class. Caverject uses a superfine needle for administration, caverject. Likewise not all side effects have necessarily been reported from this medication so you may have symptoms beyond those listed above. Cardiovascular problems- Occasionally Caverject Impulse may upset the rhythm of your heart or cause a change in blood caverject. Individuals who use alprostadil should be counselled about the protective measures that are necessary to guard against the spread of sexually transmitted diseases, caverject, including the human immunodeficiency virus HIV.

Alprostadil is present in various mammalian tissues and fluids. Click Here. General Disorders and Administration Vaverject Conditions. Although the usual contra-indication to intrapenile administration of a vasoconstrictor does not apply in the treatment of priapism, caution is advised when this option is exercised. When reconstituted, each 1ml delivers a dose of 20 micrograms of alprostadil. Sympathomimetics may reduce the effect of alprostadil. In some patients, injection of alprostadil can induce a small amount of bleeding at the site of injection. Concomitant with anticoagulants may increase inj site bleeding. At the time of discharge from the clinic, the caverject should have subsided entirely and the penis must be in a completely flaccid state. If still unsuccessful, intracavernous injection of alpha-adrenergic medication is recommended. References Australian Medicine Handbook. They should remove the needle from the syringe, discard it, and attach a new, unused sterile needle to caverject syringe. Caverject is administered by direct intracavernous injection. The next doses can be adjusted by increments of 2. Dizziness, headache or fainting. Alprostadil is not intended for co-administration with any other agent for the treatment of erectile dysfunction see Section 4. Caverject is indicated for the treatment of erectile dysfunction in adult males due to neurogenic, vasculogenic, psychogenic or mixed aetiology. The pharmacotoxic signs of alprostadil are similar in all animal species and include depression, soft stools or diarrhoea and rapid breathing, caverject. The presence caverect benzyl alcohol in caverject reconstitution vehicle decreases the degree of binding to package surfaces.

Last updated on eMC: Caverject Impulse contains the active compound alprostadil, also known as prostaglandin E1 PGE1that normally occurs naturally within the body at various sites. Show table of contents Hide table of contents 1. Blood creatinine increased, Blood pressure decreased, Heart rate increased. Caverject reconstituted, each 1ml delivers a dose of 20 micrograms of alprostadil. Reevaluate caverject 3 months. Sodium For the caverjec list of excipients, see section 6. To investigate the effect of long-term caverjecr self-injection of alprostadil Caverject on the penile circulation and return of spontaneous erection in men with arteriogenic erectile dysfunction. The intracavernosal injection must be done under caverjfct conditions. Active ingredient alprostadil. Musculoskeletal and Connective Tissue Caverject. Not applicable. The adverse drug reactions are listed in order of decreasing medical seriousness within each frequency category and system organ class. Neurogenic etiology: Caverject is administered by direct intracavernous injection. Clinical particulars 4, caverject. Peyronie's disease, Penis disorder, Erection increased. Company contact details Pfizer Limited. The usual starting dose depends on caverrject expected cause for the erectile dysfunction. To view the changes to a medicine you must sign up and log in. Nausea and dry mouth. Doses of greater than 60 micrograms of alprostadil are not recommended.

Caverject

As an alternative metaraminol may be used, but it should be noted that fatal hypertensive crises have been reported. Regular follow-up of patients, with careful examination of the penis, is strongly recommended to detect signs of penile fibrosis or Caverject disease, caverject. Initial therapy should be by penile aspiration. Caverject 20 micrograms powder for solution for injection. Dizziness, headache or fainting. Caverject 20 micrograms powder for solution for injection. Cavefject Cavererject Impulse packets come with detailed administration instructions. Painful erection is more likely to occur in patients with anatomical deformations of the penis, such as angulation, phimosis, cavernosal fibrosis, Peyronie's disease or plaques. Caverkect with penile implants should not be treated with alprostadil. The medication needs to be injected into the shaft of an outstretched penis to have an effect. Marketing authorisation holder 8. If necessary, the procedure may be repeated on the opposite side of the penis until a total of up to ml blood has been aspirated. You caverject however not use this medication if you have been advised not to have sex for health reasons. If you have any symptoms that you think may be due to the medication or that are worrying you, be sure to see your doctor. The pharmacologic effect of alprostadil in the treatment of erectile dysfunction is presumed to be mediated by inhibition of alpha 1 -adrenergic activity in penile tissue and by its relaxing effect on cavernosal smooth muscle. Excipients with known effect: By continuing to browse cacerject site you are agreeing to our policy on the use of cookies. If self-administration is planned, the physician should make an assessment caverject the patient's skill and competence with the procedure. To reconstitute Caverject using the prefilled diluent syringe: In patients infected with daverject diseases, this could increase the cavrject of such diseases to their partner. Caverject Impulse. The csverject dose should caverject be administered caverject an experienced medical practitioner but it may be cavejrect for you to learn how to self-administer for later doses.

Individuals who use alprostadil should be counselled about the protective measures that are necessary to guard against the spread of sexually transmitted diseases, including the human immunodeficiency virus HIV. To minimize the risk, select the lowest effective dose. The minimum amount of benzyl alcohol at which toxicity may occur is not known. After proper training and instruction, alprostadil may be injected at home, caverject. Blood pressure and pulse should be continuously monitored during the procedure. High doses of alprostadil 0, caverject. Such agents should not be used in combination with alprostadil due to the potential for inducing prolonged erections. Subsequent incremental increases of micrograms should be given until an optimal dose is achieved. Last updated on eMC: Penile fibrosis, including angulation, cavernosal fibrosis, fibrotic nodules and Peyronie's disease may occur following cavermect intracavernosal administration of alprostadil. Dr Joe Kosterich. The minimum amount of benzyl alcohol at which toxicity may caverject is not known. Painful erection is more likely to occur in patients with anatomical caverject of the penis, such as angulation, phimosis, cavernosal fibrosis, Peyronie's disease or plaques. Reproductive System caverject Breast Disorders. Symptomatic treatment of any systemic symptoms would be appropriate. Caverject should be used with caution caverject patients who have experienced transient ischaemic attacks or those with unstable cardiovascular disorders. Show table of contents Hide table of contents 1. Alprostadil is not intended for co-administration with any other agent for the treatment of erectile dysfunction see Section 4. No relevant information additional to that already contained in cxverject SPC. Vasculogenic, psychogenic, caverject, or mixed etiology: Initial ccaverject should be by penile aspiration.

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Active ingredient

Symptomatic treatment of any caverject symptoms would be appropriate. System Organ Class. Hot on Parenthub. Subsequent incremental increases of micrograms should be given until an optimal dose is achieved. Individuals who use alprostadil should be counselled about the protective measures that are necessary to guard against the spread of caverject transmitted diseases, including the human immunodeficiency virus HIV. Extreme caution is required in patients with coronary heart disease, uncontrolled hypertension, cerebral ischaemia, and in subjects taking monoamine oxidase inhibitors. It has a diverse pharmacologic profile, among which some of its more important effects are vasodilation, inhibition of platelet aggregation, inhibition of gastric secretion, and stimulation of intestinal and uterine smooth muscle. Patients on anticoagulants such as warfarin or heparin may have increased propensity for bleeding after the intracavernosal injection. Do caverject hesitate to see your doctor for any worrying symptoms or other concerns you have regarding this medication. If necessary, the procedure may be repeated on the opposite side of the penis until a total of up to ml blood has been aspirated. The minimum amount of benzyl alcohol at which toxicity may occur is not known. As with all superfine caverject, the possibility of needle breakage exists. Regular follow-up of patients, with careful examination of the penis, is strongly recommended to detect signs of penile fibrosis or Peyronie's disease. As with all superfine needles, the possibility of needle breakage exists. Dizziness, headache or fainting. Date of revision of the text. The patient should be instructed that, if the needle is bent, it must not be used; they should also not attempt to straighten a bent needle. Alprostadil may enhance the effects of antihypertensives, vasodilative agents, anticoagulants and platelet aggregation inhibitors. The lowest effective dose should be used. Patients should be instructed to report to a physician any erection lasting for a prolonged time period, such as 4 hours or longer. Overdosage was not observed in clinical trials with alprostadil. Marketing authorisation holder 8.

The dose that is selected for self-injection treatment should provide the patient with an erection that is satisfactory for sexual intercourse. If necessary, the procedure may be repeated on the opposite side of the penis until a total of up to ml blood has been aspirated. This information is intended for use by health professionals. For erectile dysfunction of vasculogenic, psychogenic, or mixed aetiology, the initial dose is 2. The minimum amount of benzyl alcohol at which toxicity may occur is not known. Reconstituted solutions should be used immediately and not stored. This information is intended for use by health professionals. Patients with penile implants should not be treated with alprostadil. In some patients, injection of alprostadil can induce a small amount of bleeding at the site of injection. To email a medicine you must sign up and log in. In the penis PGE1 causes an increase in blood flow due to relaxation of blood vessels and muscular tissue. Continue typing to refine. It has a diverse pharmacologic profile, among which some of its more important effects are vasodilation, inhibition of platelet aggregation, inhibition of gastric secretion, and stimulation of intestinal and uterine smooth muscle. Generally Caverject Impulse will produce an erection within minutes of its injection. Marketing authorisation number s 9. When reconstituted, each 1ml delivers a dose of 20 micrograms of alprostadil. Also remember Caverject Impulse provides no protection against sexually transmitted infections so barrier contraception methods may still be required. Sign Up Log In Cancel. The treatment of priapism prolonged erection should not be delayed more than 6 hours. Drugs used in erectile dysfunction ATC code: Neurogenic etiology: Alprostadil should be used with caution in patients who have experienced transient ischaemic attacks or those with unstable cardiovascular disorders. In some patients, injection of alprostadil can induce a small amount of bleeding at the site of injection. Following intracavernous injection of 20 micrograms of alprostadil, mean peripheral levels of alprostadil at 30 and 60 minutes after injection are not significantly greater than baseline levels of endogenous PGE 1. Therefore, a more consistent product delivery is produced when Bacteriostatic Water for Injection containing benzyl alcohol is used. Such agents should not be used in combination with alprostadil due to the potential for inducing prolonged erections. This may detumesce the penis. Peyronie's disease, Caverject disorder, Erection increased. In some patients, injection of alprostadil can induce a small amount of bleeding at the site of injection. At the time of discharge from the clinic, the erection should have subsided entirely and the penis must be in a completely flaccid state.

As an alternative metaraminol may be used, but it should be noted that fatal hypertensive crises have been reported. In the majority of the cases, penile pain was rated mild or moderate in intensity. The entire dose can be injected or for better flexibility of dosing, quarterly increments can be injected. Occasionally thickening around the injection site can cause penile deformity. It is recommended that the dose administered produces a duration of the erection not exceeding one hour. Sexual stimulation and intercourse can lead to cardiac and pulmonary events in patients with coronary heart disease, congestive heart failure or pulmonary disease. Hot on Parenthub. Current Competitions. Use of intracavernosal alprostadil offers no protection from the transmission of sexually transmitted diseases. Continue typing to refine. Back to top Pfizer Limited contact details. If your erections last longer than one hour you may need a smaller dose. Premature and low-birth weight infants may be more likely to develop toxicity. To email a medicine you must sign up and log in. If necessary, this may be followed by further aspiration of blood through the same butterfly needle. Musculoskeletal and Connective Tissue Disorders. Caverject is not intended to be mixed or coadministered with any other products. Although the usual contra-indication to intrapenile administration of a vasoconstrictor does not apply in the treatment of priapism, caution is advised when this option is exercised. Individuals who use alprostadil should be counselled about the protective measures that are necessary to guard against the spread of sexually transmitted diseases, including the human immunodeficiency virus HIV. Penile fibrotic conditions eg, anatomical deformation, angulation, cavernosal fibrosis, Peyronie's disease. The pharmacotoxic signs of alprostadil are similar in all animal species and include depression, soft stools or diarrhoea and rapid breathing. Marketing authorisation number s 9. Doses of greater than 60 micrograms of alprostadil are not recommended. Reevaluate caverject 3 months. If there is no response to the administered dose, then the next higher dose may be given within 1 hour. G04B E01 Alprostadil is cavrject in cavegject mammalian tissues and fluids. The first injections of alprostadil must be done by medically trained personnel. Following administration, any unused contents of the vial or syringe should be discarded. Nausea and dry mouth. If this still fails to resolve the priapism, urgent surgical referral for further management, which caverject include a shunt procedure, is required.